Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ D,L-Sulforaphane
An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture.
MilliporeSigma™ Calbiochem™ KN-93
A cell-permeable, reversible and competitive inhibitor of rat brain CaM kinase II (Ki = 370 nM).
MilliporeSigma™ Calbiochem™ Chk2 Inhibitor, PV1019
The Chk2 Inhibitor, PV1019 controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Bcl-2 Binding Peptide, Cell-Permeable, Negative Control
A cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.
MilliporeSigma™ Calbiochem™ InSolution™ SU5402
Inhibits the tyrosine kinase activity of FGFR1 (IC50 = 10-20μM in the presence of 1mm ATP) by interacting with the catalytic domain of FGFR1
MilliporeSigma™ Calbiochem™ Aminopeptidase N/CD13 Inhibitor
The Aminopeptidase N/CD13 Inhibitor controls the biological activity of Aminopeptidase N/CD13. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ FGF Receptor Tyrosine Kinase Inhibitor
The FGF Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 192705-79-6, controls the biological activity of FGF Receptor Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ JAK3 Inhibitor VIII, NSC114792
The JAK3 Inhibitor VIII, NSC114792 controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ cPLA2α Inhibitor II, Pyrrophenone
A cell-permeable, highly potent, and reversible inhibitor of cytosolic phospholipase A2a (IC50 = 4.2 nM).
MilliporeSigma™ Calbiochem™ Heat Shock Protein Inhibitor I
Heat Shock Protein Inhibitor I, CAS 218924-25-5 blocks the induction of HSP70, HSP72, and HSP105. Blocks the development of thermotolerance in a dose-dependent manner.
MilliporeSigma™ Calbiochem™ Urea Transporter B Inhibitor, UTBinh-14
A cell-permeable triazolothienopyrimidine compound that acts as a reversible urea transporter B-selective inhibitor (IC 50 =
MilliporeSigma™ Calbiochem™ LSD1 Inhibitor IV, RN-1,HCl
LSD1 Inhibitor IV, RN-1, HCl, is a cell-permeable potent, irreversible inhibitor of lysine specific demethylase 1 (LSD1; IC50 = 70 nM in a HRP-coupled assay using H3K4Me2 peptide substrate).
MilliporeSigma™ Calbiochem™ LY 83583
A cell-permeable, competitive inhibitor of soluble guanylate cyclase (IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ Hh Signaling Antagonist X, Itraconazole
The Hh Signaling Antagonist X, Itraconazole, also referenced under CAS 84625-61-6, controls the biological activity of Hh pathway. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Combretastatin A-4
A synthetic Combretum caffrum-derived cell-permeable stilbenoid phenol that competes with colchicine tubulin binding and interferes with tubulin polymerization as well as cellular microtubule assembly